Home

raccogliere Volpe Tirare lsd1 inhibitors in clinical trials violinista Cartello Pino

Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal  Chemistry
Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal Chemistry

New tranylcypromine derivatives containing sulfonamide motif as potent LSD1  inhibitors to target acute myeloid leukemia: Design, synthesis and  biological evaluation - ScienceDirect
New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation - ScienceDirect

LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal  of Hematology & Oncology | Full Text
LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal of Hematology & Oncology | Full Text

LSD1 inhibition induces differentiation and cell death in Merkel cell  carcinoma | EMBO Molecular Medicine
LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma | EMBO Molecular Medicine

Divalent tranylcypromine derivative as lysine-specific demethylase 1  inhibitor | SpringerLink
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor | SpringerLink

Frontiers | LSD1 Activates PI3K/AKT Signaling Through Regulating p85  Expression in Prostate Cancer Cells | Oncology
Frontiers | LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells | Oncology

Histone lysine specific demethylase 1 inhibitors - RSC Medicinal Chemistry  (RSC Publishing) DOI:10.1039/D0MD00141D
Histone lysine specific demethylase 1 inhibitors - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00141D

Pre-clinical activity of combined LSD1 and mTORC1 inhibition in  MLL-translocated acute myeloid leukaemia | Leukemia
Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia | Leukemia

Table 1 from Advances toward LSD1 inhibitors for cancer therapy. | Semantic  Scholar
Table 1 from Advances toward LSD1 inhibitors for cancer therapy. | Semantic Scholar

Irreversible TCP-based LSD1 inhibitors 19-24. | Download Scientific Diagram
Irreversible TCP-based LSD1 inhibitors 19-24. | Download Scientific Diagram

LSD1 inhibitors in clinical trials | Download Scientific Diagram
LSD1 inhibitors in clinical trials | Download Scientific Diagram

Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a |  Download Table
Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a | Download Table

Frontiers | Lysine-Specific Demethylase 1A as a Promising Target in Acute  Myeloid Leukemia | Oncology
Frontiers | Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia | Oncology

LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Semantic  Scholar
LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Semantic Scholar

LSD1 inhibitors in clinical trials. (A) Structure of TCP-based... |  Download Scientific Diagram
LSD1 inhibitors in clinical trials. (A) Structure of TCP-based... | Download Scientific Diagram

Molecules | Free Full-Text | Pharmacological Inhibition of LSD1 for Cancer  Treatment | HTML
Molecules | Free Full-Text | Pharmacological Inhibition of LSD1 for Cancer Treatment | HTML

LSD1 inhibition induces differentiation and cell death in Merkel cell  carcinoma | EMBO Molecular Medicine
LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma | EMBO Molecular Medicine

Annual review of lysine-specific demethylase 1 (LSD1/KDM1A) inhibitors in  2021 - ScienceDirect
Annual review of lysine-specific demethylase 1 (LSD1/KDM1A) inhibitors in 2021 - ScienceDirect

A proof of concept phase I/II pilot trial of LSD1 inhibition by  tranylcypromine combined with ATRA in refractory/relapsed AML patients not  eligible for intensive therapy | Leukemia
A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy | Leukemia

Natural products as LSD1 inhibitors for cancer therapy - ScienceDirect
Natural products as LSD1 inhibitors for cancer therapy - ScienceDirect

Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1  inhibition | Haematologica
Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition | Haematologica

New tranylcypromine derivatives containing sulfonamide motif as potent LSD1  inhibitors to target acute myeloid leukemia: Design, synthesis and  biological evaluation - ScienceDirect
New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation - ScienceDirect

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid  leukemia cells for retinoic acid–induced differentiation
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid–induced differentiation

Targeting histone methyltransferases and demethylases in clinical trials  for cancer therapy | Clinical Epigenetics | Full Text
Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy | Clinical Epigenetics | Full Text

GSK-LSD1, an LSD1 inhibitor, quashes SARS-CoV-2-triggered cytokine release  syndrome in-vitro | Signal Transduction and Targeted Therapy
GSK-LSD1, an LSD1 inhibitor, quashes SARS-CoV-2-triggered cytokine release syndrome in-vitro | Signal Transduction and Targeted Therapy

LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal  of Hematology & Oncology | Full Text
LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal of Hematology & Oncology | Full Text