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DNA damage checkpoint kinases in cancer | Expert Reviews in Molecular  Medicine | Cambridge Core
DNA damage checkpoint kinases in cancer | Expert Reviews in Molecular Medicine | Cambridge Core

AZD-7762 | Chk Inhibitor | MedChemExpress
AZD-7762 | Chk Inhibitor | MedChemExpress

AZD7762 | ≥99%(HPLC) | Selleck | Chk inhibitor
AZD7762 | ≥99%(HPLC) | Selleck | Chk inhibitor

The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies  impact on clinical trial design. | Semantic Scholar
The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design. | Semantic Scholar

Discovery of Checkpoint Kinase Inhibitor  (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide ( AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide  Ureas | Journal of Medicinal Chemistry
Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide ( AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas | Journal of Medicinal Chemistry

Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves  abrogation of the G2 checkpoint and inhibition of homologous  recombinational DNA repair. - Abstract - Europe PMC
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. - Abstract - Europe PMC

Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and  bone remodeling
Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

AZD7762 | ≥99%(HPLC) | Selleck | Chk inhibitor
AZD7762 | ≥99%(HPLC) | Selleck | Chk inhibitor

Phase I, dose-escalation study of AZD7762 alone and in combination with  gemcitabine in Japanese patients with advanced solid tumours | SpringerLink
Phase I, dose-escalation study of AZD7762 alone and in combination with gemcitabine in Japanese patients with advanced solid tumours | SpringerLink

The Chk1/2 inhibitor AZD7762 sensitizes SW480 colon cancer cells to... |  Download Scientific Diagram
The Chk1/2 inhibitor AZD7762 sensitizes SW480 colon cancer cells to... | Download Scientific Diagram

Temozolomide and AZD7762 Induce Synergistic Cytotoxicity Effects on Human  Glioma Cells | Anticancer Research
Temozolomide and AZD7762 Induce Synergistic Cytotoxicity Effects on Human Glioma Cells | Anticancer Research

Phase I, dose-escalation study of AZD7762 alone and in combination with  gemcitabine in Japanese patients with advanced solid tumours | SpringerLink
Phase I, dose-escalation study of AZD7762 alone and in combination with gemcitabine in Japanese patients with advanced solid tumours | SpringerLink

Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and  bone remodeling
Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

Evaluation of CHK1 activation in vulvar squamous cell carcinoma and its  potential as a therapeutic target in vitro - Wang - 2018 - Cancer Medicine  - Wiley Online Library
Evaluation of CHK1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro - Wang - 2018 - Cancer Medicine - Wiley Online Library

Cells | Free Full-Text | DNA Damage Response Inhibitors in  Cholangiocarcinoma: Current Progress and Perspectives | HTML
Cells | Free Full-Text | DNA Damage Response Inhibitors in Cholangiocarcinoma: Current Progress and Perspectives | HTML

Phase I Dose-escalation Study Of AZD7762, A Checkpoint Kinase Inhibitor, In  Combination With Gemcitabine In Patients With Advanced Solid Tumors. |  ApconiX
Phase I Dose-escalation Study Of AZD7762, A Checkpoint Kinase Inhibitor, In Combination With Gemcitabine In Patients With Advanced Solid Tumors. | ApconiX

Prexasertib - an overview | ScienceDirect Topics
Prexasertib - an overview | ScienceDirect Topics

Frontiers | Targeting BRCA and DNA Damage Repair Genes in GI Cancers:  Pathophysiology and Clinical Perspectives | Oncology
Frontiers | Targeting BRCA and DNA Damage Repair Genes in GI Cancers: Pathophysiology and Clinical Perspectives | Oncology

Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy |  Cell Death & Differentiation
Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy | Cell Death & Differentiation

Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial  carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer  Research | Full Text
Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer Research | Full Text

Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves  abrogation of the G2 checkpoint and inhibition of homologous  recombinational DNA repair. - Abstract - Europe PMC
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. - Abstract - Europe PMC

Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial  carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer  Research | Full Text
Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer Research | Full Text

CHK1 inhibitor AZD7762 alone caused more cytotoxicity to RBCC but... |  Download Scientific Diagram
CHK1 inhibitor AZD7762 alone caused more cytotoxicity to RBCC but... | Download Scientific Diagram

Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and  bone remodeling
Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial  carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer  Research | Full Text
Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine | Journal of Experimental & Clinical Cancer Research | Full Text

Effect of AR Knockdown and Chk1/2 Inhibitor AZD7762 on TopBP1-ATR-Chk1... |  Download Scientific Diagram
Effect of AR Knockdown and Chk1/2 Inhibitor AZD7762 on TopBP1-ATR-Chk1... | Download Scientific Diagram

AZD-7762
AZD-7762

Resistance to the CHK1 inhibitor prexasertib involves functionally distinct  CHK1 activities in BRCA wild-type ovarian cancer | Oncogene
Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer | Oncogene

PDF] AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint  abrogation and potentiates DNA-targeted therapies | Semantic Scholar
PDF] AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies | Semantic Scholar

Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in  osteosarcoma cells | Cancer Cell International | Full Text
Checkpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells | Cancer Cell International | Full Text